Mark M. answered 10/01/21
Retired math prof. Calc 1, 2 and AP Calculus tutoring experience.
Recall that sin(2θ) = 2sinθcosθ
So, 2sin2xcos2x = 2(sinxcosx)2 = 2[(1/2)2sinxcosx]2 = (1/2)sin2(2x)
By the Chain Rule, the derivative is (1/2)[2sin(2x)](sin(2x)}' = sin(2x)cos(2x)(2) = 2sin(2x)cos(2x) = sin(4x)