If you plug in 2 to f'(x) you will get:
f'(2) = -5f(2)(3+f(2)) = -5*4(3+4) = -140 grams/minute
We need to convert this rate to grams per second which can be done by divide -140 by 60 to give you a rate of -2.333 grams/second. Now to get estimate the final answer you just do 4 - 2.333 because we're assuming the solid will lose about 2.333 grams every second. Therefore, one second later the solid will have about 1.667 grams.