Mark M. answered 07/15/20
Retired math prof. Calc 1, 2 and AP Calculus tutoring experience.
By the Mean Value Theorem, there is at least one number, c, in the interval (1,6) such that
f'(c) = [f(6) - f(1)]/ (6 - 1)
So, f(6) - f(1) = 5f'(c).
Since 2 ≤ f'(c) ≤ 4, 10 ≤ 5f'(c) ≤ 20
So, f(6) - f(1) is between 10 and 20.