Side effects of ivermectin and anti-hypertensive drugs?

Question

Are there any side effects when the drug Ivermectin and anti-hypertensive drugs are taken together? I'm only asking out of curiosity. I worked briefly as an intern with US-AIDS for the control and eradication of onchocerciasis in West Africa.

Answer 1

As far as the mechanism of Ivermectin (which is disrupting cell membrane of parasite to cause its death), it does not directly affect blood pressure from a theoretical point of view. However, in post marketing studies, Ivermectin may cause tachycardia (fast heart rate) in some people (reported in 4% of people) so not too common. Usually you would only take 1-2 doses of ivermectin, so the significance of this is further limited. In addition, Ivermectin pretty much does not have any interaction with other medications. Hope that answers your question.