If you really mean that the whole parenthesis beginning with -3 is the exponent:
then f'(x) = 5{-3(2x5-3x3-4)[-3(10x4 - 9x2)]x^[-3(2x5 - 3x3-4)-1].
For the second one I will tell you a mnemonic I learned recently:
downsie d upsie - upsie d downsie divided by downsie squeared