Peter R. answered 11/28/22
Experienced Instructor in Prealgebra, Algebra I and II, SAT/ACT Math.
Best way to estimate is to convert all terms into one-digit multiples of powers of 10. Then use rules of exponents to do the multiplication and division.
3851 ≅ 4 x 103
40308 x 10-12 ≅ 4 x 10-8
0.0019 x 1014 ≅ 2 x 1011
0.000039 ≅ 4 x 10-5
(4 x 103)(4 x 10-8) = 16 x 10-5
(2 x 1011)(4 x 10-5) = 8 x 106
(16 x 10-5)/(8 x 106) = 2 x 10-11