Vertex form is y= a(x-h)^2 +k where h and k are the x and y coordinates of the vertex And a is scale factor
so y=a(x-4)^2+2
To solve for a use the given point (2,-6)
-6 =a(2-4)^2 +2
-8 =a(-2)^2
-8= a(4)
a=-2
So final equation is y=-2(x-4)^2 +2
You can verify by graphing the equation and you will see its vertex is at(4,2) and it passes thru the point (2,-6)