Use the explicit formula for an arithmetic sequence:
an = a1 + d·(n-1)
We are given a16 = 88 and d = -5:
an = a1 + d·(n-1)
88 = a1 + (-5)·(16-1)
Solve for a1. To find the sum of the first 45 terms, use the sum formula for n = 45:
S = n(a1+an)/2
You just found the value of a1 above. To find a45, use the explicit formula above given that you now know a1, d, and n (=45)
a45 = a1 + (-5)(45-1) = ?