Vertex form:
y = a(x-h)2 + k
(h,k) = (-4,-1) (given)
y = a(x-(-4))2 + (-1)
y = a(x+4)2 - 1
To find a, plug in the known point (-6,3):
y = a(x+4)2 - 1
3 = a(-6+4)2 - 1
Solve for a. If you need to, multiply the final vertex form out and combine like-terms to put it into standard form.