which of the following functional groups would need to be protected to avoid reacting with grignard reagent?

Question

which of the following functional groups would need to be protected to avoid reacting with Grignard reagent?

a) alcohol

B) ether

c) alkyne

d) aryl

e) alkene

Answer 1

With Grignard reagents, typically you will want to protect alcohol groups since they can react to form a new carbon-oxygen bond, making an alkoxide compound. (this is called "Transmetalation")