Edward C. answered 10/29/19
Caltech Grad for math tutoring: Algebra through Calculus
When you find an integral by substitution, you are essentially doing the Chain Rule (for differentiation) in reverse.
Recall the Chain Rule says that if h(x) = f(g(x)), then h'(x) = f'(g(x))*g'(x).
So if you have an integrand that contains both a function g(x) and its derivative g'(x), it can sometimes be useful to try the substitution u = g(x), with du = g'(x)dx.
For example, if you were trying to find ∫sin3(x)cos(x)dx, you might notice that both sin(x) and its derivative cos(x) appear in the integrand. So let u = sin(x), then du = cos(x)dx and the integral becomes ∫u3du, which is simply (1/4)u4 + C = (1/4)sin4(x) + C.
So do you see any functions in your integrand that also have their derivative present as well (to within a constant factor, which can always be pulled outside the integral)?