Inspecting 16x(8x2 + 9)4, one realizes that 16x is the derivative of 8x2 + 9.
To build the integral, first increase the power of (8x2 + 9) from 4 to 5.
Then supply (1)(8x2 + 9)5 with a coefficient that will multiply by the power exponent 5 to produce 1.
Stand (1/5) or 0.2 by (8x2 + 9)5 to obtain 0.2(8x2 + 9)5.
Make a test differentiation of 0.2(8x2 + 9)5 which goes to (0.2)(5)(16x + 0)(8x2 + 9)(5-1).
Simplify (0.2)(5)(16x + 0)(8x2 + 9)(5-1) to 16x(8x2 + 9)4, the integrand given in the problem statement.
The Indefinite Integral is then written as ∫16x(8x2 + 9)4dx = 0.2(8x2 + 9)5 + C (where C represents some exact number, as opposed to a variable number, that will vanish to 0 when differentiated).