Explanation of the terms "downstream signaling" and "upstream signaling"?

In molecular biology, what's the meaning of the terms "downstream signaling" and "upstream signaling"? What's the difference between them?

Is monogamy a human innate behaviour?

As the question states, got curious and I was wondering if monogamy is an innate human behaviour or is it because of how we built society (religion, traditions, etc.)? Let's say we go back in time,... more

What's the mechanism for being mentally tired?

I notice that after long tests, or long periods of critical thinking, my body and mind feel noticeably tired. Why does this happen? Are the neurons in my head not firing as quickly, or is there... more

What is a fructose derived carbon?

Here it is in context----> Although hepatocytes possess the enzymatic machineries to convert fructose-derived carbon into glucose, glycogen, lactate, lipid, carbon dioxide, and/or other... more

How do ion channels transport only specific ions?

Ion channels, such as $Na^+$ channels and $K^+$ channels, are higly specific for ion permeability. But how do these channels achieve and maintain this specificity? Like how does a $K^+$ channel... more

10/04/15

Which of the following is NOT a correct statement about passive transport across the cell membrane

Which of the following is NOT a correct statement about passive transport across the cell membrane? a) Diffusion across an electrochemical gradient is one form of passive transport. b) Facilitated... more

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