2 Answered Questions for the topic heterocyclic compounds

07/09/19

Why is the exo product formed in the Diels–Alder reaction between furan and maleic anhydride?

For most Diels–Alder reactions, the major product is *endo* because there are favourable interactions between the newly forming pi bond and the electron withdrawing groups of the dienophile. Why... more

06/24/19

Why are fluorides more reactive in nucleophilic aromatic substitutions than bromides?

In nucleophilic aromatic substitution reactions, why do fluorides react faster than bromides? Ordinarily bromide is a better leaving group than fluoride, e.g. in $\\mathrm{S_N2}$ reactions, so why... more

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