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Review Questions for Glycogen Metabolism

Glycogen Metabolism

Describe the structure of glycogen.

Where is glycogen found in the body? Does it provide different physiological functions in each place?

Describe the reactions catalyzed by each of the following enzymes during glycogen catabolism:
  • Glycogen Phosphorylase
  • Debranching Enzyme
  • Phosphoglucomutase

What are the energy requirements for glycogen catabolism?

Describe the reactions catalyzed by each of the following enzymes during glycogen synthesis:
  • Glycogenin
  • Glycogen Synthase
  • Branching Enzyme

What energetically favorable hydrolysis reaction drives glycogen synthesis?

How does the body avoid a futile cycle of glycogen synthesis and metabolism.

Explain how epinephrine and glucagon regulate glycogen synthase.

Compare insulin’s effect on glycogen synthase with its effect on glycogen phosphorylase.

Webpages with multiple choice and study questions:
http://faculty.une.edu/com/courses/bionut/distbio/obj-512/Chap28-practice%20questions.htm
http://cbc.arizona.edu/classes/bioc460/spring/460web/questions/Exam4-StudyQues.key.html

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