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histamines are released when the skin blocks germs from entering the immune system

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Joseph C. | Joseph, Trilingual instructor, Paso Robles, CAJoseph, Trilingual instructor, Paso Robl...
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The answer is TRUE.

Histamine is involved in local immune responses as well as regulating some physiological functions. As part of an immune response to foreign pathogens, histamine is produced by white blood cells. Histamine increases the permeability of the capillaries to white blood cells, and allows them to engage pathogens in the infected tissues.